Synthesis and Biological Activity of Drug Delivery System Based on Chitosan Nanocapsules
نویسندگان
چکیده
منابع مشابه
Polymer-based nanocapsules for drug delivery.
A review of the state of knowledge on nanocapsules prepared from preformed polymers as active substances carriers is presented. This entails a general review of the different preparation methods: nanoprecipitation, emulsion-diffusion, double emulsification, emulsion-coacervation, polymer-coating and layer-by-layer, from the point of view of the methodological and mechanistic aspects involved, e...
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The most important characteristics of chitosans, which make them useful as delivery vectors for drugs and therapeutic proteins, are their excellent mucoadhesive and absorption enhancing properties [1-3]. The mucoadhesion is due to the electrostatic interaction between the positive charge on the chitosan polymer and the negatively charged sialic acid residues on the mucosal surface [4]. Because ...
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The polymeric nanoparticles are prepared from biocompatible polymers in size between 10-1000 nm. Chitosan is a biocompatible polymer that - can be utilized as drug delivery systems. In this study, chitosan nanoparticles were synthesized using an optimized spontaneous emulsification method. Determining particle size and morphology are two critical parameters in nanotechnology. The aim of this st...
متن کاملInvestigation of Size and Morphology of Chitosan Nanoparticles Used in Drug Delivery System Employing Chemometric Technique
The polymeric nanoparticles are prepared from biocompatible polymers in size between 10-1000 nm. Chitosan is a biocompatible polymer that - can be utilized as drug delivery systems. In this study, chitosan nanoparticles were synthesized using an optimized spontaneous emulsification method. Determining particle size and morphology are two critical parameters in nanotechnology. The aim of this st...
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ژورنال
عنوان ژورنال: Advances in Nanoparticles
سال: 2014
ISSN: 2169-0510,2169-0529
DOI: 10.4236/anp.2014.34019